Background & Aim.Sphincter-saving rectal surgery is prone to cause changes in bowel function associated with Low Anterior Resection Syndrome (LARS).Our aim was to assess LARS-like symptoms within a population of 50-80-year old in order to understand the functional disturbances and emotional impact of LARS.Materials and methods: We used a questionna
T Cell-Tumor Interaction Directs the Development of Immunotherapies in Head and Neck Cancer
The competent immune system controls disease effectively due to induction, function, and regulation of effector lymphocytes.Immunosurveillance is exerted mostly by cytotoxic T-lymphocytes (CTLs) while specific immune suppression is associated with tumor malignancy and progression.In squamous cell carcinoma of the head inmi and neck, the presence, a
Lane-Changing Tracking Control of Automated Vehicle Platoon Based on MA-DDPG and Adaptive MPC
To address the problem of autonomous lane-changing maneuvers for automated vehicle platoons on highways, a novel platoon lane-changing (PLC) tracking control framework based on the multi-agent Deep Deterministic Policy Gradient (MA-DDPG) and adaptive model predictive control (AMPC) is presented.Currently, the classic platoon cooperative control met
Immunotherapy for lung adenocarcinoma patients with bone metastases: who really needs it
BackgroundLung adenocarcinoma patients are often found to have developed bone metastases at the time of initial diagnosis.With the continuous development of technology, we have successfully entered the era of immunotherapy.This study aimed to determine the efficacy of immunotherapy in lung adenocarcinoma patients with bone metastases (LABM) through
The Concept of Circular Economy in Wastewater Management along the Slovenian Coast
The current concept of wastewater management and treatment in the European Union complies with the requirements of Directive 91/271/EEC on urban wastewater treatment, established in 1991 with a primary focus on limiting excessive organic carbon, nitrogen, and phosphorus in treated water.At that time, the reuse of treated water was not considered.No